Border forces at the Port of Plymouth have seized around 100kg of cocaine after an operation was carried out by officers on site.
The discovery was made after officers searched a lorry containing concentrated orange juice that had arrived on a ferry from Santander, Spain.
It has been predicted that the total street-value of the drugs will run into millions of dollars.
A 62-year-old man from the Manchester area of the UK was arrested and later bailed until November, pending further inquiries.
The UK National Crime Agency’s (NCA) Border Policing Command is currently investigating the smuggling attempt.
Speaking on behalf of the NCA, Peter Avery said: “This was a very significant seizure of cocaine worth millions which has been prevented from reaching the streets. It represents a significant dent in the profits of the criminals responsible.”